Top Healthcare Companies In USA

The healthcare industry is one of the largest in the US. It makes up more than 18.3% of the country’s GDP. Many thousands of companies work together to generate this income. However, some top healthcare companies have become household names in America. 

These influential brands can benefit many B2B businesses to grow and earn more money. Further, the USA stands in 3rd position in the global market. So, focusing on companies can help reach a broader audience.   

B2B company owners looking for better reach can connect with the largest healthcare companies in the USA. It will help them enter this lucrative market with ease.

Discover the Top Healthcare Companies in USA

The healthcare sector goes beyond just medical care and health. The US healthcare market covers many other domains related to well-being. It includes pharmaceuticals, insurance, medical supplies, medical instruments, etc. 

In fact, in 2021, the US healthcare market totaled $808 billion. These numbers show why promoting healthcare products/services for B2B businesses is worthwhile.   


Now, let’s explore the 10 largest healthcare companies spread across different health segments in the USA. 

  • UnitedHealth Group
  • CVS Health Corp
  • The Cigna Group
  • McKesson Corp
  • Pfizer Inc.
  • Cencora Inc
  • Centene Corp
  • Cardinal Health Inc    
  • Walgreens Boots Alliance Inc.
  • Baxter International

1. UnitedHealth Group


Market Cap: $497.95B  
Revenue: $359.98 B 
Company Size: 10,001+  

Being one of the leading names in healthcare and well-being, UnitedHealth Group is at the top. This Minnesota-based company runs two main units: Optum and UnitedHealthcare. Under both units, the company aims to make high-quality care more affordable and within everyone’s reach.  

Their key offerings are:  

  • Optum Health: It provides care using technology and data. It directly connects with healthcare providers, local medical groups with the necessary tools and direction. 
  • UnitedHealthcare: It is an insurance and managed care company. Under this unit, they sell health insurance plans and services. These plans and services cater to employers, businesses, government, and individuals. 

UnitedHealth Group came into existence in 1977 and has provided essential products and services to everyone.  

2. CVS Health Corp


Market Cap: $103.41 B
Revenue: $347.80 B
Company Size: 300,000+

CVS Health Corp is a well-known pharmacy chain that is among the top 100 healthcare companies in the USA by revenue. It is also one of the largest pharmacy benefits managements (PMB) companies.  

Over the years, CVS Health Corp has become an integrated healthcare provider with high-value services. Its solutions cover: 

  • Healthcare and wellness products  
  • Beauty products  
  • Personal care products  
  • Disease management  
  • Administrative services 

The organization offers high-quality care, helping people regulate their emotional and physical well-being. They also enable accessible healthcare with initiatives like MinuteClinics and HealthHUB.  

Customers can also get their services through online applications. These include:  

  • CVS Caremark (Convenient prescription refill)  
  • CVS Pharmacy (Healthcare and wellness shop)  
  • Athena Health App (Life insurance) 
  • CVS Specialty (Specialized medication support) 

3. The Cigna Group


Market Cap: $91.55 B
Revenue: $189.85 B
Company Size: 71,300+

The third company in this top 10 healthcare companies in USA list is Cigna Corp. The healthcare company has a massive global reach, serving people in over 30 countries.  

Cigna offers managed healthcare and insurance products via two divisions. They are  

  • Cigna Healthcare: It offers complete and cost-efficient plans and solutions. It allows patients to access medical care, specialty medications, wellness benefits, vision care, and more.   
  • Evernorth Health Services: It specializes in pharmacy, value-based care, and benefits management solutions. It also provides medical benefits management to healthcare facilities and organizations, helping them improve patient care and clinical workflows.    

Cigna Group’s primary services include health and dental insurance. It also covers disability, life, and accident insurance with different budget options. The company offers these plans via employers and other groups like governments, unions, and associations.  

4. McKesson Corp


Market Cap: $291.09 B
Revenue: $189.85 B
Company Size: 51,000+

McKesson is a company focused on making a difference. Its solutions and products cover almost every healthcare space. They have retail pharmacies, long-term care sites, and home care agencies. The company also develops surgical tools and medicines.  

Being one of the biggest healthcare companies, it offers wholesale medical supplies and equipment. It also has units for medicines distribution and healthcare tech solutions.  

The company covers four types of business segments in this space: 

  • US Pharmaceutical: This company focuses on wholesale drug distribution and value-added technology solutions. It serves health systems, community providers, specialty clinics, and retail pharmacies. 
  • Prescription Technology Solutions: This company brings together providers, pharmacies, payers, and biopharma. The goal is to improve access to medication. There is also a need to solve adherence problems. 
  • Medical-Surgical Solutions: Provides medical-surgical supplies and logistics services to healthcare providers. It offers coverage for several healthcare places. These include nursing homes, labs, nursing homes and centers for surgery. 
  • International: Offers services to wholesale, retail, and institutional customers in Europe and Canada.  

5. Pfizer Inc.


Market Cap: $163.238B
Revenue: $99.9 billion
Company Size: 83,000

Most people around the world know about this company. Pfizer is amongst the largest healthcare companies in the USA. The company is involved in manufacturing biopharmaceuticals.  

It develops many popular pharmacy products under its name. Common medicines like Advil, Lyrica, Bextra, and Robitussin are all Pfizer products. Further, many fast-selling consumer products like Chapstick and Preparation-H are also Pfizer-made.  

The brand also offers solutions for cardiovascular problems, women’s health issues, and more. It even mass-produces penicillin and vaccines to manage rare diseases. Some of the other key Pfizer pharmaceutical products are: 

  • Zoloft: SSRI (selective serotonin reuptake inhibitors) antidepressant 
  • Lipitor: Cholesterol medicine 
  • Chantix: Smoking cessation drug 
  • Viagra: Erectile dysfunction drug 
  • Xanax: Psychoactive medicine 
  • Prevnar 13: Vaccine to prevent pneumonia 

While it is a New York-based firm, China, Japan, India, Ireland, Belgium, and Singapore also have Pfizer branches. It runs units in 180 countries and produces more than 350 different pharmaceuticals.

6. Cencora Inc


Market Cap: $42.97 B
Revenue: $262.17 B
Company Size: 46,000+

Formerly AmerisourceBergen Corp, Cencora is a pharmaceutical sourcing and distribution organization. Its headquarters is in Chesterbrook, Pennsylvania. 

They help doctors, medical staff, and drug manufacturers improve patient care and provide access to necessary medicines. It designs future-forward solutions to increase supply chain efficiency, covering human and animal health.  

Cencora handles around 20% of the medicines and medical supplies in the country.  

The organization is a distributor of several healthcare products. These include generic, over the counter, branded as well as specialty categories. 

Its home healthcare supplies, equipment, and related products are popular. Most hospitals, pharmacies, medical clinics, and long-term care facilities rely on these supplies.  

Cencora also offers data analytics, staffing, pharmacy management, and software solutions to help clients upgrade their services. Here are some other segments Cencora covers under its support services: 

  • Clinical trial logistics 
  • Cell and gene therapy support 
  • Pharmacy and physician practice solutions 
  • Biosimilars education, solutions, and support 
  • Veterinary and livestock management optimization 

7. Centene Corp


Market Cap: $41.68 B
Revenue: $150.10 B
Company Size: 10,001+

Did you know Centene ranks 25th on the Fortune 500 list of largest US corporations by revenue? This healthcare firm provides services to government-sponsored programs. It has two main segments:  

  • Managed Care: This vertical offer health plan coverage to people through government-subsidized initiatives. It covers benefits like primary and specialty physician care and Inpatient and outpatient hospital care.  
  • Specialty Services: This segment covers different services and products. It serves healthcare facilities, state programs, correction services, employer groups, and other businesses. 

8. Cardinal Health Inc


Market Cap: $25.63 B
Revenue: $210.17 B
Company Size: 48,000+

With more than 50 years of experience, Cardinal Health serves nearly 90% of all hospitals in the United States. The company also services more than 60 K US pharmacies and 10 K specialty physician clinics.  

It supplies pharmaceuticals, equipment, and lab products in Dublin, Ohio. The company also provides end-to-end healthcare solutions and data-driven insights. These services help medical companies simplify operations and offer high-value services or solutions.  

Cardinal Health covers two main segments: 

  • Pharmaceutical: This segment distributes generic and branded pharmaceuticals, time-sensitive radiopharmaceuticals, and over-the-counter healthcare products.  
  • Medical: This segment manufactures and sources branded and specialty medical, laboratory, and surgical products and devices.  

It also offers technology and business solutions to specialty clinics, private practices, and hospitals.

9. Walgreens Boots Alliance Inc.


Market Cap: $21.27B
Revenue: $210.17 B
Company Size: 330,000

Walgreens Boots Alliance is an integrated healthcare, retail, and pharmacy company that offers medication, beauty, and personal care products as well as health and wellness services.  

The company divides its services into three key segments. These are: 

  • US Retail Pharmacy: It covers the operations of retail drug stores under the brand name Walgreens and Duane Reade. This section offers mail and central specialty pharmacy services. It uses digital platforms and offline stores to serve the facilities. 
  • International Segment: It focuses on the health and beauty retail business outside the country and covers the distribution and wholesale of pharmaceuticals in Germany.  
  • US Healthcare Segment: It covers personalized and fair whole-person services. It partners with other healthcare companies, such as VillageMD and BrightSpring Health Services. 

10. Baxter International


Market Cap: $20.50 B
Revenue: $14.95 B
Company Size: 330,000

Baxter International helps improve patient outcomes for healthcare providers and caregivers by developing innovative products and services for different healthcare facilities and patients. 

As one of the top healthcare companies in USA, Baxter functions in America, Africa, Europe, the Middle East, and Asia-Pacific. It supplies the products through a network of independent distributors. They also work with specialty pharmacies, wholesalers, and direct salespersons.  

Some of Baxter International’s product offerings to ensure smarter and personalized care:  

  • Sterile intravenous solutions
  • Acute and chronic dialysis therapies
  • Infusion systems and devices
  • Inhaled anesthetics
  • Advanced surgical equipment
  • Smart bed systems
  • Surgical hemostat and sealant products

Final Words

In the United States, several multinational healthcare companies focus on different aspects of healthcare, from medical supplies to health insurance and pharmaceuticals to medical care.

Nonetheless, all these top healthcare companies in USA account for a major portion of the country’s gross domestic product. They play a key role in driving the US healthcare industry forward with their innovation and dedication to improving healthcare.

B2B businesses targeting the healthcare industries will find these healthcare companies a profitable avenue to explore. They are the largest healthcare companies in the USA, constantly striving to provide cutting-edge solutions and influence the lives of patients every day. Reaching out to them will yield positive results and increase your healthcare business sales.

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